Regional distribution of excess tissue mass in ARDS lung
نویسندگان
چکیده
منابع مشابه
Regional physiology of ARDS
The acute respiratory distress (ARDS) lung is usually characterized by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas. This inhomogeneity is normally caused by the presence of lung edema and/or anatomical variations, and is deeply influenced by the gravitational forces.For...
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VAT, kg 6-cm Up a 0.36±0.26 0.18±0.10 0.52±0.25 6-cm Mid a 0.36±0.26 0.18±0.10 0.51±0.25 6-cm Down a 0.34±0.18 0.21±0.09*† 0.45±0.17*† IHL, mmol/kg wet wt 36.4±34.4 22.4±22.9 48.5±38.2 FFA-b, mM 0.59±0.22 0.55±0.26 0.62±0.17 TG-b, mg/dl a 71.4±38.2 58.4±25.7 80.4±43.0 Glucose-b, mg/dl 99.7±10.1 95.1±6.9 103.0±10.8 a p<.05: NO vs. OB; p<.05: *vs. 6-cm Up, † vs. 6-cm Mid, ‡ vs. 6-cm Down. Abdomin...
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Ventilator-induced lung injury (VILI) consists of tissue damage and a biological response resulting from the application of inappropriate mechanical forces to the lung parenchyma. The current paradigm attributes VILI to overstretching due to very high-volume ventilation (volutrauma) and cyclic changes in aeration due to very low-volume ventilation (atelectrauma); however, this model cannot expl...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2015
ISSN: 1364-8535
DOI: 10.1186/cc14324